Worldwide, an estimated 55.4 million people died in 2019Trusted Source, with chronic disorders that advance slowly accounting for 74% of those deaths. The fact that many of the deadliest diseases are largely preventable may be even more shocking. 

The location of a person's home, their availability to preventive treatment, and the calibre of their medical care are all non-preventable factors that affect risk. However, there are a number of actions that everyone can take to reduce their risk.

1. Ischemic heart disease
Ischemic heart disease also called as Coronary artery disease is the deadliest illness in the world (CAD). CAD, also known as ischemic heart disease, happens when the blood channels that provide blood to the heart narrow. Arrhythmias, heart failure, and chest discomfort can result from untreated CAD. 

Plaque buildup in the walls of the coronary arteries, which provide blood to the heart and other parts of the body, results in CAD. Deposits of cholesterol and other materials in the artery form plaque. Over time, plaque development causes the interior of the arteries to thin, which can either completely or partially obstruct blood flow. Atherosclerosis is the name of this process. 

The most prevalent sign of CAD is angina, or discomfort and pain in the chest. Angina can develop when arteries get narrowed by an excessive buildup of plaque. Because they can obstruct blood flow to your heart muscle and the rest of your body, narrowed arteries can lead to chest pain.

 A heart attack is frequently the first indication that a person has CAD. Angina (chest pain or discomfort), weakness, lightheadedness, nausea, and cold sweats are all signs of a heart attack. Symptoms also include shortness of breath, arm or shoulder pain, or other discomfort.
CAD can weaken the heart muscle over time. Heart failure is a serious condition where the heart is unable to pump blood as effectively as it should. Risk factors for CAD include being overweight, not exercising, eating poorly, and smoking.

 Additionally, having a family history of heart illness—especially early-onset heart disease—increases your risk of developing coronary artery disease (CAD) (50 or younger). Your medical team may check your blood pressure, blood cholesterol, and blood sugar levels to determine your risk for developing coronary artery disease (CAD).

 For anyone suffering from a heart attack, heart failure, or other heart condition that requires surgery or medical attention, cardiac rehabilitation (rehab) is a crucial therapy. Cardiovascular rehabilitation can enhance quality of life and help these people avoid having another heart episode.